Chematek
SYNHYDRID®

A New Standard in High Yield Reduction Chemistry

The most effective organometallic reducing agent available
/SAFE AND EFFECTIVE

The most effective organometallic reducing agent available

Synhydrid® is a highly versatile organometallic reducing agent that is safe and easy to handle. It is best known for a number of classic transformations and for its ability to replace more reactive and hazardous chemicals such as DIBAL & Lithium Aluminium Hydride (LAH).

The Synhydrid® Difference

The Synhydrid® Difference

Chematek understands that it is imperative that shelf life, stability and efficacy are always maintained. Our product is as safe and effective as the day it was first manufactured.

Chematek customers can use Synhydrid® without any pre-treatment, warming, mixing or any other unnecessary manual handling.

Compare Synhydrid®

See how Synhydrid® measures up against the alternatives.

  • Due to higher concentration with no losses to residues.

  • No unwanted by-products.

  • Product remains stable from -50C to +170C.

  • No side reactions.

  • Non pyrophoric so it’s easy to handle and use. This reduces accidents, safety compliance and handling issues.

  • Under correct storage conditions the product is ultra-stable over long time periods and temperature extremes. It has a minimum 24 months shelf life.

  • Can be used across multiple synthesis reactions. This means you only need to hold one reducing agent.

  • Less spent on safety and handling of other reducing agents.

Key Reactions

REDUCTION REACTIONS

Synhydrid® performs reduction reactions, transforming functional groups by means of hydride addition. It can reduce esters and acids to alcohols or aldehydes, amides and nitriles to amines, lactones to diols or lactols.

A VERSATILE INITIATOR

Synhydrid® is also a versatile initiator in anionic polymerisation of Caprolactam. It can also be used to initiate Grignard reactions smoothly and effectively.

TO ALCOHOLSTO ALDEHYDESTO AMINES
ESTER → ALCOHOLESTER → ALDEHYDENITRILE → AMINE
ALDEHYDE → ALCOHOLNITRILE → ALDEHYDEAMIDE → AMINE
ACID CHLORIDE → ALCOHOLACID CHLORIDE → ALDEHYDEIMINE → AMINE
KETONE → ALCOHOL
ANHYDRIDE → ALCOHOL

MODIFIED SYNHYDRID®

For increased safety and greater selectivity.

Synhydrid® APIs

This is just a snapshot of our full API selection. Get in touch today to find out about our full range.

Alongside our current APIs, we’re also working hand-in-hand with customers and partners to expand the Synhydrid® API universe. Visit our Modified Synhydrid® page to find out more and contact us about your requirements and upcoming projects.

APIAPPLICATION
AGOMELATINEANTIDEPRESSANT
ALFENTANILANALGESIC
APREPITANTANTI VOMITING
ARTENIMOL (DIHYDROARTEMISININ)ANTI MALARIA
ASENAPINEANTIPSYCHOTIC
ATAZANAVIRANTIRETROVIRAL
ATOMOXETINE (TOMOXETINE)ATTENTION DEFICIT HYPERACTIVITY DISORDER
ATORVASTATINANTI CHOLESTEROL

Synhydrid® Applications

We are also working with companies on new applications for modified Synhydrid® across a range of new industries.

Can you capitalize on the huge benefits of using Synhydrid® to establish a competitive advantage for your business?

Eliminate Supply Chain Disruption

Eliminate Supply Chain Disruption

Scalable Production Capacity

The world's largest volume production facility (2000mt per annum), with easily expandable capacity if required.

Multiple Production Sites

Multiple Production Sites

Continuous supply from two co-located sites.

Always Available Stock

Always Available Stock

200mt minimum stock available for delivery at all times.

No Stoppages

No Stoppages

State-of-the-art production facilities ensures no stoppages for regulatory changes and equipment maintenance.

Localised Supply

Localised Supply

Multiple global warehousing to ensure stock is always on-hand.

Cost Efficiency

Cost Efficiency

Supply in local currency for reduced admin resources and cash flow.

Container Management & Packaging Options

Container Disposal

No need to manage container disposal with our returnable container shuttle service.

Custom Quantities

Avoid problems with dosage and residues during production cycles with containers custom filled to exact quantities.

Batch Size Matching

Choice of different size non-returnable packaging for exact batch size matching.

15KG

15KG

25KG

25KG

50KG

50KG

200KG

200KG

1000KG

1000KG

World Class Manufacturing

Synhydrid® is manufactured by Lučební závody a.s. Kolín, a respected chemical manufacturer in the Czech Republic that has been operating for over 150 years. Lučební are the original manufacturers of sodium dihydridobis(2-methoxyethoxo)aluminate and their brand, Synhydrid® has a global reputation for stability and quality. Chematek are proud to represent Lučební as the exclusive global distribution partner for the product.

Reduction Chemistry Experts

Reduction Chemistry Experts

Recognizing the potential of Synhydrid® in the early 2000s, Lučební appointed Chematek as their Exclusive Global Distribution Partner.

With supply chain integrity and market development a priority, Chematek were chosen for their expertise in reduction chemistry, worldwide networks and global distribution skills.

Increasing Demand

Increasing Demand

Lučební recognise the need for a stable supply line of high quality product and by 2025 will have increased Synhydrid® production capacity to 3000 MT per year. This includes multiple production lines designed to insulate customers from any supply chain disruptions.

THE CHEMATEK DIFFERENCE

EXPERTISE FROM EXPERIENCE

Four Divisions. One Team

Synhydrid® is one of the flagship products from boutique industrial services company Chematek.

Chematek is a boutique industrial services company, operating four distinct but interlinked product divisions: Fine Chemicals, Petro Chemicals, Lubricants and Oil & Gas Engineering, Procurement and Construction.

The specialist services provided by each division are enriched by our diverse, cross divisional knowledge and deep functional expertise. Our diversity gives us unique and transferable insights which enable us to deliver better product solutions for our clients. Our boutique scale means that every client is highly valued and our team of experts are easily accessible.

  • REACH accreditation

  • Full technical support

  • Global logistics network

  • Demonstrated plant safety

  • Dedicated R&D team with in-house laboratories

  • Experienced track record in hard to find, difficult to manage Fine Chemicals

  • Exclusive R&D partnerships with large clients

  • Assured systems and handling

  • Customs and Documentation

  • Strategic warehouse network

Request a Sample

Thank you for your interest in Synhydrid®. If you would like to work directly with us, we can supply samples for appropriate research and development projects. Please fill out the form below.

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