15KG
SYNHYDRID®
Advancing Reduction Chemistry: How Synhydrid® Outperforms Lithium Aluminium Hydride
/SAFE AND EFFECTIVE
All the Power of LiAlH₄ — Without the Risk
Synhydrid® is a high-performance reducing agent developed to meet the rigorous demands of modern synthesis. Designed as a safe, efficient alternative to lithium aluminium hydride (LiAlH₄) and DIBAL-H, it is used across key sectors including pharmaceuticals, flavours and fragrances, agrochemicals, and polymer chemistry.
Reduced Costs Are Not The Only Advantage
Lithium aluminium hydride (LiAlH₄) and diisobutylaluminium hydride (DIBAL-H) are both considerably more expensive per kilogram than Synhydrid®.
Yet price tells only part of the story—Synhydrid® also offers significant operational benefits. Alongside savings from the improved safety profile, it is compatible with more economical solvent options like toluene and xylenes. Lower usage volumes from higher hydridic hydrogen efficiency means less material is needed, reducing waste and overall consumption. Long shelf life under ambient dry conditions simplifies inventory management and reduces losses.
POWERFUL CONTROLLED REACTIVITY
Delivers reduction performance comparable to LiAlH₄—without the associated safety and handling challenges.
NON-PYROPHORIC
Synhydrid® is air-stable and non-pyrophoric, eliminating the spontaneous ignition risk of LiAlH₄. It ensures a safer working environment for labs and production sites.
EXTENDED SHELF LIFE
Stable in dry conditions with no loss of efficacy over time—supporting better stock control and reducing waste.
EASY TO HANDLE AND TRANSPORT
Supplied in liquid form, Synhydrid® can be transferred using standard pumps or inert gas pressure systems. It avoids the complex handling requirements of powder-based reductants.
BROAD SOLVENT COMPATIBILITIES
Offers excellent solubility in a wide range of solvents, including cost-effective aromatics such as toluene and xylenes. This contrasts with the strict ether requirements of LiAlH₄.
PROVEN ACROSS INDUSTRIES
Trusted in industrial synthesis for its consistent performance and safety profile, Synhydrid® supports scalable, reliable reductions from lab to plant.
Case Study
Example Reaction: Reduction of Methyl Laurate
The reduction of methyl laurate with a 33% stoichiometric excess of SDMA (Synhydrid®) or lithium aluminium hydride (LiAlH₄) at 0 °C in diethyl ether yields 95% of dodecanol in just one minute — identical performance for both reducing agents.
However, when comparing material efficiency and cost, the difference becomes clear. The molar weight of LiAlH₄ is 37.955 g/mol, while SDMA has a molar weight of 202.162 g/mol. Commercially, LiAlH₄ products typically contain 95% active ingredient, whereas Synhydrid® solutions contain 70% SDMA by weight.
While the LiAlH₄ molecule contains twice the amount of hydridic hydrogen compared to the SDMA molecule, cost and material efficiency are better evaluated by considering the quantity of commercial product needed to deliver one mole of hydridic hydrogen.
A simple calculation demonstrates this:
LiAlH₄ (95%) → (37.955 / 4) / 0.95 = 10.0 g required per mole of hydridic hydrogen
Synhydrid® (70%) → (202.162 / 2) / 0.70 = 144.4 g required per mole of hydridic hydrogen
Despite the higher weight of material needed, Synhydrid® delivers identical reaction efficiency and yield under milder, safer, and more manageable conditions, offering a compelling economic and operational advantage over LiAlH₄ in real-world reduction processes.
Flexible Packaging Formats
Available in a range of packaging options to suit different process requirements. Synhydrid® is typically available in the following packaging
formats, designed to accommodate a range of operational scales and safety requirements:
25KG
50KG
200KG
1000KG
Dive Deeper Into Synhydrid
Comparative Analysis of Sodium Borohydride and Synhydrid®
Download our whitepaper paper to discover advanced insights into the reactivity, stability, and solubility of Synhydrid® compared with metal hydride-reducing agents like Sodium Borohydride and Lithium Aluminium Hydride.
Comparative Analysis WhitepaperThe Complete Guide to Synhydrid® & Piperhydride
Discover the potential of Synhydrid® and Piperhydride® as reducing agents in organic synthesis.
Complete Guide To Synhydrid
Let's Talk
If you have a project you’d like to discuss, please provide your details below so we can chat.
Request a Sample
Thank you for your interest in Synhydrid®. If you would like to work directly with us, we can supply samples for appropriate research and development projects. Please fill out the form below.